ea0025p112 | Cytokines, growth factors, neuroendocrinology and behaviour | SFEBES2011
Meakin Paul
, Winter Johnathan
, Ashford Mike
, McNeilly Alison
Alzheimers disease (AD) is one of the most common causes of dementia world wide. Accumulation of β-amyloid (Aβ) has been implicated as a causal factor of AD. Beta secretase (BACE1) catalyses the rate limiting step in the production Aβ and has been postulated as a potential therapeutic target for AD treatment. Environmental factors, including psychological stress, accelerate the development of dementia and AD. This study examined hypothalamicpituitary...